AMPCs_EN_202201_V3

Proof of Concept § Chronic Kidney Disease (CKD) Estimated Glomerular Filtration Rate (eGFR) • Indicates the ability of kidneys to filter waste from blood and measures overall kidney function • Deteriorates as they age • eGFR values lower than 15 require dialysis CKD Stages eGFR （ mL/min/m 2 ) Stage 1: Mild kidney damage with normal kidney function ≧ 90 Stage 2 ： Kidney damage with mild loss of kidney function 60-89 Stage 3: Mild to moderate kidney damage with equal loss of kidney function 30-59 Stage 4 Severe loss of kidney function 15-29 Stage 5: Kidney failure ＜ 15